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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYH11 All Species: 27.27
Human Site: S1444 Identified Species: 85.71
UniProt: P35749 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35749 NP_002465.1 1972 227339 S1444 D N Q R Q L V S N L E K K Q R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001109425 1979 227586 S1451 D N Q R Q L V S N L E K K Q R
Dog Lupus familis XP_862291 1938 223405 S1444 D N Q R Q L V S N L E K K Q K
Cat Felis silvestris
Mouse Mus musculus O08638 1972 227010 S1444 D N Q R Q L V S N L E K K Q K
Rat Rattus norvegicus Q9JLT0 1976 228947 S1444 D H Q R Q I V S N L E K K Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508844 1972 227342 S1444 D N Q R Q L V S N L E K K Q K
Chicken Gallus gallus P10587 1979 228777 S1450 D N Q R Q L V S N L E K K Q K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q99323 2057 236625 L1528 E A Q R T K V L E L E K K Q K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.5 96.1 N.A. 95.9 75.7 N.A. 94.3 89.8 N.A. N.A. N.A. 58.1 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 97.3 97.5 N.A. 98.5 88.3 N.A. 97.6 95.2 N.A. N.A. N.A. 74.8 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 80 N.A. 93.3 93.3 N.A. N.A. N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 0 0 0 0 0 0 0 13 0 100 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 13 0 0 0 0 0 100 100 0 75 % K
% Leu: 0 0 0 0 0 75 0 13 0 100 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 75 0 0 0 0 0 0 88 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 100 0 88 0 0 0 0 0 0 0 0 100 0 % Q
% Arg: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 25 % R
% Ser: 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _